皮包 (pí bāo) literally combines 皮 (pí), meaning 'skin' or 'leather', and 包 (bāo), meaning 'bag' or 'purse'. Together, it refers specifically to a bag made of leather—commonly used for handbags, briefcases, or small satchels. Unlike generic terms like 包 (bāo) or 手提包 (shǒutíbāo), 皮包 emphasizes the material, implying durability, quality, and often a more formal or traditional aesthetic.

This word is widely used in everyday speech and shopping contexts, especially when distinguishing leather goods from synthetic alternatives like 布包 (bùbāo, cloth bag) or 塑料包 (sùliàobāo, plastic bag). It appears frequently in advertisements, department store signage, and conversations about accessories or personal belongings. While historically associated with animal hides (hence its inclusion under 'Animals'), modern usage focuses on the material property rather than the source.