'Syndrome' in English, zōng hé zhēng is a medical term referring to a group of signs and symptoms that consistently occur together and indicate a particular disease or disorder. The three characters combine meaningfully: zōng (comprehensive, integrated), hé (unified, combined), and zhēng (manifestation, symptom or sign). Together, they convey the idea of multiple features 'integrated' into a recognizable clinical pattern.

This word is used exclusively in formal medical contexts — in diagnoses, textbooks, research papers, and clinical discussions. It is never used colloquially or for non-medical groupings of traits. Common examples include 'Down syndrome' (唐氏综合征), 'metabolic syndrome' (代谢综合征), and 'post-traumatic stress syndrome' (创伤后应激综合征). Unlike general terms like zhèngzhuàng (symptom), zōng hé zhēng implies a specific, named constellation with diagnostic significance.